基因名称(Gene Name)
CNNM4 ACDP4 KIAA1592
免疫原
Synthesized peptide derived from human CNNM4 AA range: 18-68
特异性
This antibody detects endogenous levels of CNNM4 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.358% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)
背景
This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta. [provided by RefSeq, Feb 2010],
功能
function:Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions.,miscellaneous:Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo.,similarity:Belongs to the ACDP family.,similarity:Contains 2 CBS domains.,subunit:Interacts with COX11.,tissue specificity:Widely expressed. Highly expressed in heart.,
