基因名称(Gene Name)
DACT2 C6orf116 PP13671
免疫原
Synthesized peptide derived from human DACT2 AA range: 239-289
特异性
This antibody detects endogenous levels of DACT2 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.355% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Dapper homolog 2 (Dapper antagonist of catenin 2)
背景
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
功能
domain:The C-terminal PDZ-binding motif may mediate interaction with the PDZ domains of DSH (Dishevelled) family proteins.,function:Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors.,similarity:Belongs to the dapper family.,
