基因名称(Gene Name)
FTSJD1 AFT
免疫原
Synthesized peptide derived from human FTSJ1 AA range: 462-512
特异性
This antibody detects endogenous levels of FTSJ1 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.334% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
FtsJ methyltransferase domain-containing protein 1 (EC 2.1.1.-) (Protein adrift homolog)
背景
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010],
功能
similarity:Belongs to the methyltransferase superfamily. RrmJ family.,
