基因名称(Gene Name)
ZER1 C9orf60 ZYG ZYG11BL
免疫原
Synthesized peptide derived from human ZER1 AA range: 388-438
特异性
This antibody detects endogenous levels of ZER1 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.318% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Protein zer-1 homolog (Hzyg) (Zyg-11 homolog B-like protein)
背景
This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012],
功能
function:Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.,similarity:Belongs to the zyg-11 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,similarity:Contains 5 ARM repeats.,subunit:Interacts with the TCEB1-TCEB2/Elongin BC complex. Part of an E3 ubiquitin ligase complex including ZER1, CUL2 and Elongin BC.,tissue specificity:Expressed in testis, spermatocytes and spermatides (at protein level). Expressed in spermatocytes, spermatides, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.,
