基因名称(Gene Name)
UTP14C KIAA0266
免疫原
Synthesized peptide derived from human UT14C AA range: 493-543
特异性
This antibody detects endogenous levels of UT14C at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.317% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
U3 small nucleolar RNA-associated protein 14 homolog C
背景
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008],
功能
function:Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis.,miscellaneous:Encoded by an autosomal retrotransposed copy of the X-linked gene UTP14A. Evolution of autosomal retrogenes from X-linked progenitors compensates for X-chromosome silencing during male meiosis.,similarity:Belongs to the glycosyltransferase 1 family.,similarity:Belongs to the UTP14 family.,tissue specificity:Expressed in testis.,
