基因名称(Gene Name)
PHTF1 PHTF
免疫原
Synthesized peptide derived from human PHTF1 AA range: 122-172
特异性
This antibody detects endogenous levels of PHTF1 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.298% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Putative homeodomain transcription factor 1
背景
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A(KIR2DL5A) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the
功能
function:May play a role in transcription regulation.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with FEM1B.,tissue specificity:Widely expressed with highest levels in testis.,
