免疫原
Synthesized peptide derived from human GMIP AA range: 421-471
特异性
This antibody detects endogenous levels of GMIP at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.282% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
GEM-interacting protein (GMIP)
背景
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
功能
function:Stimulates, in vitro and in vivo, the GTPase activity of RhoA.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 Rho-GAP domain.,subunit:Interacts with GEM through its N-terminal.,
