基因名称(Gene Name)
MDGA2 MAMDC1 UNQ8188/PRO23197
免疫原
Synthesized peptide derived from human MDGA2 AA range: 726-776
特异性
This antibody detects endogenous levels of MDGA2 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.240% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1)
背景
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced tr
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May involved in cell-cell interactions.,similarity:Contains 1 MAM domain.,similarity:Contains 6 Ig-like (immunoglobulin-like) domains.,
