基因名称(Gene Name)
ZC3H3 KIAA0150 ZC3HDC3
免疫原
Synthesized peptide derived from human ZC3H3 AA range: 818-868
特异性
This antibody detects endogenous levels of ZC3H3 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.200% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Zinc finger CCCH domain-containing protein 3
背景
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
功能
similarity:Contains 5 C3H1-type zinc fingers.,