免疫原
Synthesized peptide derived from human F227A AA range: 429-479
特异性
This antibody detects endogenous levels of F227A at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.180% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
eukaryotic translation elongation factor 1 delta(EEF1D) Homo sapiens This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010],
功能
function:EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the EF-1-beta/EF-1-delta family.,subunit:EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.,
