免疫原
Synthesized peptide derived from human ZN583 AA range: 437-487
特异性
This antibody detects endogenous levels of ZN583 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.176% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Zinc finger protein 583 (Zinc finger protein L3-5)
背景
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012],
功能
function:May be involved in transcriptional regulation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 12 C2H2-type zinc fingers.,
