基因名称(Gene Name)
ZNF675 TIZ
免疫原
Synthesized peptide derived from human ZN675 AA range: 66-116
特异性
This antibody detects endogenous levels of ZN675 at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.162% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Zinc finger protein 675 (TRAF6-binding zinc finger protein) (TRAF6-inhibitory zinc finger protein)
背景
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016],
功能
function:May be involved in transcriptional regulation. May play a role during osteoclast differentiation by modulating TRAF6 signaling activity.,similarity:Contains 1 KRAB domain.,similarity:Contains 15 C2H2-type zinc fingers.,subunit:Interacts with TRAF6.,
