基因名称(Gene Name)
RNF220 C1orf164
免疫原
Synthesized peptide derived from human RN220 AA range: 218-268
特异性
This antibody detects endogenous levels of RN220 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.137% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
E3 ubiquitin-protein ligase RNF220 (EC 6.3.2.-) (RING finger protein 220)
背景
The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011],
功能
similarity:Contains 1 RING-type zinc finger.,