基因名称(Gene Name)
OCSTAMP C20orf123
免疫原
Synthesized peptide derived from human OCSTP AA range: 488-538
特异性
This antibody detects endogenous levels of OCSTP at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.136% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Osteoclast stimulatory transmembrane protein (OC-STAMP)
背景
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008],
功能
function:The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.,mass spectrometry:This is the measured mass for the GINS complex PubMed:17557111,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the GINS2/PSF2 family.,subunit:Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS3. GINS complex interacts with DNA primase in vitro.,
