基因名称(Gene Name)
INSM2 IA6 Nbla106
免疫原
Synthesized peptide derived from human INSM2 AA range: 8-58
特异性
This antibody detects endogenous levels of INSM2 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.133% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Insulinoma-associated protein 2 (Zinc finger protein IA-6)
背景
domain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,
功能
function:May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.,similarity:Contains 5 C2H2-type zinc fingers.,
