基因名称(Gene Name)
CARS2 OK/SW-cl.10
免疫原
Synthesized peptide derived from human SYCM AA range: 95-145
特异性
This antibody detects endogenous levels of SYCM at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.121% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)
背景
This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of cysteine to tRNA molecules. A splice-site mutation in this gene has been associated with a novel progressive myoclonic epilepsy disease with similar symptoms to MERRF syndrome. [provided by RefSeq, Mar 2015],
功能
catalytic activity:ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the class-I aminoacyl-tRNA synthetase family.,
