基因名称(Gene Name)
SLC1A6 EAAT4
免疫原
Synthesized peptide derived from human EAA4 AA range: 320-370
特异性
This antibody detects endogenous levels of EAA4 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.118% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (Solute carrier family 1 member 6)
背景
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010],
功能
function:Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,tissue specificity:Brain. Expressed densely and selectively in cell bodies of Purkinje cells.,
