基因名称(Gene Name)
KLF2 LKLF
免疫原
Synthesized peptide derived from human KLF2 AA range: 196-246
特异性
This antibody detects endogenous levels of KLF2 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.70% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Krueppel-like factor 2 (Lung krueppel-like factor)
背景
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011],
功能
function:Binds to the CACCC box in the beta-globin gene promoter and activates transcription.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with WWP1.,
