基因名称(Gene Name)
PNMA1 MA1
免疫原
Synthesized peptide derived from human PNMA1 AA range: 14-64
特异性
This antibody detects endogenous levels of PNMA1 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.39% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Paraneoplastic antigen Ma1 (37 kDa neuronal protein) (Neuron- and testis-specific protein 1)
背景
This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors. [provided by RefSeq, Feb 2014],
功能
miscellaneous:Antibodies against PNMA1 are present in sera from patients suffering of paraneoplastic neurological disorders.,similarity:Belongs to the PNMA family.,subcellular location:In tumor cells, it is cytoplasmic.,tissue specificity:Testis and brain specific. In some patients suffering from cancers, it is also specifically expressed by the paraneoplastic tumor cells.,
