免疫原
Synthesized peptide derived from human MRM1 AA range: 119-169
特异性
This antibody detects endogenous levels of MRM1 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.37% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial large ribosomal RNA ribose methylase)
背景
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
功能
function:Probably methylates the ribose of guanosine G-2270 in the peptidyl transferase center of the mitochondrial large ribosomal RNA (21S).,similarity:Belongs to the RNA methyltransferase trmH family.,
