基因名称(Gene Name)
BRIX1 BRIX BXDC2
免疫原
Synthesized peptide derived from human BRX1 AA range: 15-65
特异性
This antibody detects endogenous levels of BRX1 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.28% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
背景
function:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.,similarity:Contains 4 EF-hand domains.,subcellular location:Translocates to the plasma membrane upon calcium binding.,subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit.,
功能
function:Required for biogenesis of the 60S ribosomal subunit.,similarity:Belongs to the BXDC2/BRX1 family.,similarity:Contains 1 Brix domain.,
