免疫原
Synthesized peptide derived from human SPEB AA range: 266-316
特异性
This antibody detects endogenous levels of SPEB at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.25% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Agmatinase, mitochondrial (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH)
背景
The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmodulin-binding domain. The encoded protein may be a transcriptional coactivator of genes involved in cardiac growth. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010],
功能
catalytic activity:Agmatine + H(2)O = putrescine + urea.,cofactor:Manganese .,pathway:Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine (ADC route): step 1/1.,similarity:Belongs to the arginase family. Agmatinase subfamily.,tissue specificity:Highly expressed in liver and kidney. Also found in skeletal muscle, fetal liver, brain, testis, skin and the gastrointestinal tract.,
