免疫原
Synthesized peptide derived from human NUD13 AA range: 182-232
特异性
This antibody detects endogenous levels of NUD13 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.21% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Nucleoside diphosphate-linked moiety X motif 13 (Nudix motif 13) (EC 3.-.-.-) (Protein KiSS-16)
背景
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2013],
功能
similarity:Contains 1 nudix hydrolase domain.,tissue specificity:Highly expressed in metastasis-suppressed chromosome 6 melanoma hybrids.,
