基因名称(Gene Name)
TMOD2 NTMOD
免疫原
Synthesized peptide derived from human TMOD2 AA range: 138-188
特异性
This antibody detects endogenous levels of TMOD2 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.13% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
背景
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008],
功能
function:Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.,similarity:Belongs to the tropomodulin family.,subunit:Binds to the N-terminus of tropomyosin and to actin.,tissue specificity:Neuronal-tissue specific.,
