基因名称(Gene Name)
SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL
蛋白名称
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
免疫原
Synthesized peptide derived from part region of human protein
特异性
SCRIB Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
功能
similarity:Contains 4 PDZ (DHR) domains.,
