基因名称(Gene Name)
PLIN2 ADFP
蛋白名称
Perilipin-2 (Adipophilin) (Adipose differentiation-related protein) (ADRP)
免疫原
Synthesized peptide derived from part region of human protein
特异性
PLIN2 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011],
功能
lipid transport, response to organic substance, lipid localization, response to organic cyclic substance, monocarboxylic acid transport, organic acid transport, fatty acid transport, long-chain fatty acid transport, lipid storage, response to drug, carboxylic acid transport,
