蛋白名称
Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase)
免疫原
Synthesized peptide derived from part region of human protein
特异性
CEGT Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014],
功能
catalytic activity:UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.,function:Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".,online information:GlycoGene database,pathway:Lipid metabolism; sphingolipid metabolism.,similarity:Belongs to the glycosyltransferase 2 family.,tissue specificity:Found in all tissues examined.,
