蛋白名称
Transketolase (TK) (EC 2.2.1.1)
免疫原
Synthesized peptide derived from part region of human protein AA range: 125-175
特异性
TKT Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012],
功能
catalytic activity:Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.,cofactor:Binds 1 calcium ion per subunit.,cofactor:Binds 1 thiamine pyrophosphate per subunit.,disease:Has been implicated in the latent genetic disease Wernicke-Korsakoff syndrome (WKS) [MIM:277730]. WKS causes specific brain damage.,online information:Transketolase entry,similarity:Belongs to the transketolase family.,subunit:Homodimer.,
