基因名称(Gene Name)
WDFY1 KIAA1435 WDF1 ZFYVE17
蛋白名称
WD repeat and FYVE domain-containing protein 1 (FENS-1) (Phosphoinositide-binding protein 1) (WD40- and FYVE domain-containing protein 1) (Zinc finger FYVE domain-containing protein 17)
免疫原
Synthesized peptide derived from part region of human protein
特异性
WDFY1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
The protein encoded by this gene is a phosphatidylinositol 3-phosphate binding protein, which contains a FYVE zinc finger domain and multiple WD-40 repeat domains. When exogenously expressed, it localizes to early endosomes. Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain. [provided by RefSeq, Jan 2015],
功能
similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 7 WD repeats.,subunit:Binds PtdIns3P in vitro with high specificity over other phosphoinositides.,
