背景
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010],
功能
ovarian follicle development, tissue homeostasis, hair follicle development, reproductive developmental process,cellular amino acid derivative metabolic process, biogenic amine metabolic process, phospholipid metabolic process,glycerophospholipid metabolic process, phosphatidylcholine biosynthetic process, ectoderm development, sex differentiation, positive regulation of cell proliferation, gonad development, epidermis development, female gonad development, lipid biosynthetic process, phospholipid biosynthetic process, response to wounding, organophosphate metabolic process, molting cycle process, hair cycle process, ovulation cycle process, respiratory tube development,lung development, hair follicle morphogenesis, multicellular organism reproduction, tube development, wound healing,regulation of cell proliferation, molting cycle, ethanolamine and derivative metabolic process, homeostat