基因名称(Gene Name)
BGN SLRR1A
蛋白名称
Biglycan (Bone/cartilage proteoglycan I) (PG-S1)
免疫原
Synthesized peptide derived from human protein . at AA range: 110-190
特异性
PGS1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
ELP2; STATIP1; Elongator complex protein 2; ELP2; SHINC-2; STAT3-interacting protein 1; StIP1
背景
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015],
功能
function:May be involved in collagen fiber assembly.,PTM:The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class I subfamily.,similarity:Contains 12 LRR (leucine-rich) repeats.,subunit:Homodimer. Forms a ternary complex with MFAP2 and ELN.,tissue specificity:Found in several connective tissues, especially in articular cartilages.,
