蛋白名称
Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45)
免疫原
Synthesized peptide derived from human protein . at AA range: 20-100
特异性
MEPE Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
STAC2; SH3 and cysteine-rich domain-containing protein 2; 24b2/STAC2; Src homology 3 and cysteine-rich domain-containing protein 2
背景
This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
功能
function:Seems to play a role in mineralization.,tissue specificity:Expressed by osteoblasts. Secreted from oncogenic hypophosphataemic tumours.,
