蛋白名称
SLIT and NTRK-like protein 4
免疫原
Synthesized peptide derived from human protein . at AA range: 130-210
特异性
SLIK4 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
SEPT2; DIFF6; KIAA0158; NEDD5; Septin-2; Neural precursor cell expressed developmentally down-regulated protein 5; NEDD-5
背景
This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
功能
function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 18 LRR (leucine-rich) repeats.,tissue specificity:Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, gliobastomas and primitive neuroectodermal tumors.,
