基因名称(Gene Name)
FLRT2 KIAA0405 UNQ232/PRO265
蛋白名称
Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin-like domain-containing leucine-rich transmembrane protein 2)
免疫原
Synthesized peptide derived from human protein . at AA range: 170-250
特异性
FLRT2 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
fibronectin leucine rich transmembrane protein 2(FLRT2) Homo sapiens This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
功能
function:May have a function in cell adhesion and/or receptor signaling.,PTM:N-glycosylated.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed in pancreas, skeletal muscle, brain, and heart.,
