蛋白名称
Lymphocyte antigen 86 (Ly-86) (Protein MD-1)
免疫原
Synthesized peptide derived from human protein . at AA range: 80-160
特异性
LY86 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
function:May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.,induction:In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS).,subcellular location:Associated with CD180 at the cell surface.,subunit:Binds CD180.,tissue specificity:Highly expressed in B-cells, monocytes and tonsil.,
功能
function:May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.,induction:In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS).,subcellular location:Associated with CD180 at the cell surface.,subunit:Binds CD180.,tissue specificity:Highly expressed in B-cells, monocytes and tonsil.,
