蛋白名称
Activator of apoptosis harakiri (BH3-interacting domain-containing protein 3) (Neuronal death protein DP5)
免疫原
Synthesized peptide derived from part region of human protein AA range: 1-50
特异性
HRK Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
harakiri, BCL2 interacting protein(HRK) Homo sapiens This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
功能
domain:The BH3 motif is required for the induction of cell death.,function:Activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L).,
