基因名称(Gene Name)
BMPER KIAA1965
蛋白名称
BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2)
免疫原
Synthesized peptide derived from human protein . at AA range: 440-520
特异性
BMPER Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011],
功能
function:Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.,similarity:Contains 1 TIL (trypsin inhibitory-like) domain.,similarity:Contains 1 VWFD domain.,similarity:Contains 5 VWFC domains.,subunit:Interacts with BMP4.,tissue specificity:Highly expressed in lung, and brain and also in primary chondrocytes.,
