基因名称(Gene Name)
PCOLCE PCPE1
蛋白名称
Procollagen C-endopeptidase enhancer 1 (Procollagen COOH-terminal proteinase enhancer 1) (PCPE-1) (Procollagen C-proteinase enhancer 1) (Type 1 procollagen C-proteinase enhancer protein) (Type I proco
免疫原
Synthesized peptide derived from human protein . at AA range: 170-250
特异性
PCOC1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008],
功能
function:Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.,function:C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity.,PTM:C-terminally processed at multiple positions.,similarity:Contains 1 NTR domain.,similarity:Contains 2 CUB domains.,
