基因名称(Gene Name)
CFHR1 CFHL CFHL1 CFHL1P CFHR1P FHR1 HFL1 HFL2
蛋白名称
Complement factor H-related protein 1 (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36)
免疫原
Synthesized peptide derived from part region of human protein
特异性
FHR1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009],
功能
function:Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.,PTM:N-glycosylated. Two forms are observed; one with a single side chain and the other with two.,similarity:Contains 5 Sushi (CCP/SCR) domains.,tissue specificity:Expressed by the liver and secreted in plasma.,
