基因名称(Gene Name)
SPINT1 HAI1 UNQ223/PRO256
蛋白名称
Kunitz-type protease inhibitor 1 (Hepatocyte growth factor activator inhibitor type 1) (HAI-1)
免疫原
Synthesized peptide derived from part region of human protein
特异性
SPIT1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008],
功能
domain:This inhibitor contains two inhibitory domains.,function:Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 MANSC domain.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,
