蛋白名称
Transcription factor SOX-4
免疫原
Synthesized peptide derived from part region of human protein
特异性
SOX4 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
SRY-box 4(SOX4) Homo sapiens This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008],
功能
function:Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Interacts with UBE2I.,tissue specificity:Testis, brain, and heart.,
