基因名称(Gene Name)
IGFBPL1 IGFBPRP4
蛋白名称
Insulin-like growth factor-binding protein-like 1 (IGFBP-related protein 10) (Insulin-like growth factor-binding-related protein 4) (IGFBP-rP4)
免疫原
Synthesized peptide derived from part region of human protein
特异性
IBPL1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
function:IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.,induction:Down-regulated in multiple tumors.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 Kazal-like domain.,tissue specificity:Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung.,
功能
function:IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.,induction:Down-regulated in multiple tumors.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 Kazal-like domain.,tissue specificity:Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung.,
