基因名称(Gene Name)
CITED2 MRG1
蛋白名称
Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG-1) (P35srj)
免疫原
Synthesized peptide derived from human protein . at AA range: 190-270
特异性
CITE2 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2(CITED2) Homo sapiens The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
功能
function:Interferes with the binding of transcription factors HIF-1a and STAT2 to p300/CBP.,induction:By hypoxia and deferoxamine.,similarity:Belongs to the CITED family.,subunit:Binds to the p300/CBP CH1 region.,
