蛋白名称
Disrupted in renal carcinoma protein 1 (Disrupted in renal cancer protein)
免疫原
Synthesized peptide derived from human protein . at AA range: 20-100
特异性
DIRC1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene consists of two exons and encodes a 104aa protein. Disruption of this gene by translocation t(2;3)(q33;q21) is associated with familial clear cell renal cancer. [provided by RefSeq, Sep 2010],
功能
disease:A chromosomal aberration involving DIRC1 is found in familial renal cell carcinoma 1-related translocation t(2;3)(q33;q21) (RCC1).,tissue specificity:Expressed at low steady-state level in adult placenta, testis, ovary, prostate, fetal kidney, spleen and skeletal muscle.,
