蛋白名称
T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56)
免疫原
Synthesized peptide derived from part region of human protein
特异性
TBR1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015],
功能
function:Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain development.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Brain.,
