基因名称(Gene Name)
CCNK CPR4
免疫原
Synthesized peptide derived from human protein . at AA range: 80-160
特异性
CCNK Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities. [provided by RefSeq, Jul 2008],
功能
function:May play a role in transcriptional regulation. In vitro, is associated with a kinase activity toward both RNA polymerase II C-terminal domain and CDK2 (CAK).,similarity:Belongs to the cyclin family. Cyclin C subfamily.,subunit:Part of a cyclin-kinase pair in the RNA polymerase II holoenzyme. Binds to CDK9.,tissue specificity:Ubiquitously expressed. Highest levels in testis.,
