蛋白名称
WD repeat-containing protein 44 (Rabphilin-11)
免疫原
Synthesized peptide derived from part region of human protein
特异性
WDR44 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a protein that interacts with the small GTPase rab11. A similar protein in rat binds the GTP-containing active form of rab11. This protein may play a role in endosome recycling. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
功能
function:Downstream effector for RAB11. May be involved in vesicle recycling.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 WD repeats.,subcellular location:Colocalized with RAB11 along microtubules oriented toward lamellipodia.,subunit:Interacts with the GTP-bound form of RAB11 when membrane-associated. Does not bind to other Rab and Rho small G proteins.,
