基因名称(Gene Name)
LBX1 LBX1H
蛋白名称
Transcription factor LBX1 (Ladybird homeobox protein homolog 1)
免疫原
Synthesized peptide derived from human protein . at AA range: 70-150
特异性
LBX1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by RefSeq, Jul 2008],
功能
function:Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with LBXCOR1 which acts as a transcriptional corepressor.,
