蛋白名称
Sjoegren syndrome/scleroderma autoantigen 1 (Autoantigen p27)
免疫原
Synthesized peptide derived from part region of human protein
特异性
SSA27 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. [provided by RefSeq, Jul 2008],
功能
function:Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,
