基因名称(Gene Name)
RHOXF1 OTEX PEPP1
蛋白名称
Rhox homeobox family member 1 (Ovary-, testis- and epididymis-expressed gene protein) (Paired-like homeobox protein PEPP-1)
免疫原
Synthesized peptide derived from human protein . at AA range: 110-190
特异性
RHXF1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene is a member of the PEPP subfamily of paired-like homoebox genes. The gene may be regulated by androgens and epigenetic mechanisms. The encoded nuclear protein is likely a transcription factor that may play a role in human reproduction. [provided by RefSeq, Dec 2012],
功能
domain:Mutagenesis of amino acids 147 to 164 and 155 to 164 lead to a major cytoplasmic localization, with only minor localization in the nucleus.,function:May be a transcription factor involved in reproductive processes.,induction:By androgen.,similarity:Belongs to the paired-like homeobox family. PEPP subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Does not interact with itself.,tissue specificity:Ovary, testis and epididymis. Also detected in the prostate and the mammary gland. Expressed in many tumor cell lines derived from acute lymphocytic leukemia, prostate, endometrial adenocarcinoma, melanoma, bladder carcinoma, colon carcinoma, erythroleukemia and breast carcinoma. Not expressed in placenta.,
